WHAT IS NCI MATCH

NCI MATCH is also known as MATCH.

It is a precision medicine clinical trial, where cancer patients are assigned to receive treatment based on genetic changes found in their tumors. This is done mainly through genomic sequencing ( laboratory method that is used to determine the genetic form of cancer cells).

Patients whose tumors have genetic changes that match one of the treatments in the trial may receive that treatment, if they meet other eligibility criteria.

The NCI MATCH trial determines whether treating cancer based on these specific genetic changes is effective, regardless of cancer type.

The drugs included in the trial are:

• Either approved by the U.S. Food and Drug Administration (FDA) for another cancer.

or

• Still being tested in other clinical trials but have shown some effectiveness against tumors with a particular genetic change.

PrIMe test is based on the same methods to determine the most efficient treatment for a cancer patient.

Patients whose tumors have genetic changes that match one of the treatments in the trial may receive that treatment, if they meet other eligibility criteria

The NCI MATCH trial determines whether treating cancer based on these specific genetic changes is effective, regardless of cancer type.

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